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The effect of oncomodulin on cAMP phosphodiesterase activity.

作者信息

Klee C B, Heppel L A

出版信息

Biochem Biophys Res Commun. 1984 Nov 30;125(1):420-4. doi: 10.1016/s0006-291x(84)80384-8.

DOI:10.1016/s0006-291x(84)80384-8
PMID:6095845
Abstract

Oncomodulin was purified from Morris rat hepatoma according to the procedure of Durkin, J.P., Brewer, L.M. and MacManus, J.P. (1983) Cancer Res. 43, 5390-5394. The preparation, in general, had the properties and amino acid composition of the material which they described. However, we were unable to confirm the reported stimulation of cyclic nucleotide phosphodiesterase under conditions where calmodulin gave the usual stimulation.

摘要

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