• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Activity of DNase associated with replication of Epstein-Barr virus in NPC-204 cells.

作者信息

Liu M Y, Chen J Y, Yang C S

出版信息

Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1984 Aug;17(3):121-30.

PMID:6096087
Abstract

A deoxyribonuclease derived from Epstein-Barr virus (EBV)-producing lymphoblastoid cell line (NPC-204 cells) treated with IUdR was purified by DEAE cellulose, phospho-cellulose, and DNA-cellulose columns with 45% recovery. The activity of the DNase was neutralized by serum of patient with nasopharyngeal carcinoma (NPC). The DNase had a strong requirement for divalent cations and an alkaline pH optimum. Its activity was inhibited by highly ionic strength and polyamines.

摘要

相似文献

1
Activity of DNase associated with replication of Epstein-Barr virus in NPC-204 cells.
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1984 Aug;17(3):121-30.
2
Use of bacterially-expressed antigen for detection of antibodies to the EBV-specific deoxyribonuclease in sera from patients with nasopharyngeal carcinoma.
J Virol Methods. 1993 Nov;45(1):49-66. doi: 10.1016/0166-0934(93)90139-i.
3
Purification of Epstein-Barr virus associated DNase with affinity chromatography of nasopharyngeal carcinoma patient serum.
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1990 Feb;23(1):34-43.
4
Expression of the DNase encoded by the BGLF5 gene of Epstein-Barr virus in nasopharyngeal carcinoma epithelial cells.爱泼斯坦-巴尔病毒BGLF5基因编码的脱氧核糖核酸酶在鼻咽癌上皮细胞中的表达。
Virology. 1996 Aug 1;222(1):64-74. doi: 10.1006/viro.1996.0398.
5
High-level expression of the Epstein-Barr virus alkaline deoxyribonuclease using a recombinant baculovirus: application to the diagnosis of nasopharyngeal carcinoma.
Virology. 1991 Mar;181(1):390-4. doi: 10.1016/0042-6822(91)90511-9.
6
Immunological characterization of the Epstein-Barr virus phosphoprotein PP58 and deoxyribonuclease expressed in the baculovirus expression system.在杆状病毒表达系统中表达的爱泼斯坦-巴尔病毒磷蛋白PP58和脱氧核糖核酸酶的免疫学特性
Int J Cancer. 1991 Jul 30;48(6):879-88. doi: 10.1002/ijc.2910480615.
7
Antibody to Epstein-Barr virus-specific DNase in patients with nasopharyngeal carcinoma.鼻咽癌患者中针对爱泼斯坦-巴尔病毒特异性脱氧核糖核酸酶的抗体。
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1982 Nov;15(4):255-61.
8
Alkaline deoxyribonuclease induced with diterpene ester TPA and n-butyrate in Epstein-Barr virus genome-carrying Raji cells.在携带爱泼斯坦 - 巴尔病毒基因组的拉吉细胞中，由二萜酯佛波醇酯（TPA）和丁酸盐诱导产生的碱性脱氧核糖核酸酶
Intervirology. 1985;23(1):55-60. doi: 10.1159/000149567.
9
Immunological studies on the Epstein-Barr virus encoded alkaline deoxyribonuclease found in virus-producing lymphoblastoid cells.对在产生病毒的淋巴母细胞样细胞中发现的爱泼斯坦-巴尔病毒编码的碱性脱氧核糖核酸酶的免疫学研究。
J Gen Virol. 1991 Feb;72 ( Pt 2):399-404. doi: 10.1099/0022-1317-72-2-399.
10
Purification and properties of Epstein-Barr virus DNase expressed in Escherichia coli.在大肠杆菌中表达的爱泼斯坦-巴尔病毒脱氧核糖核酸酶的纯化及特性
J Virol. 1990 Jan;64(1):96-104. doi: 10.1128/JVI.64.1.96-104.1990.

引用本文的文献

1
The characterization of the EBV alkaline deoxyribonuclease cloned and expressed in E. coli.在大肠杆菌中克隆并表达的EBV碱性脱氧核糖核酸酶的特性分析。
Nucleic Acids Res. 1989 Oct 11;17(19):7609-22. doi: 10.1093/nar/17.19.7609.