Zabarovsky E R, Chumakov I M, Prassolov V S, Kisselev L L
Gene. 1984 Oct;30(1-3):107-11. doi: 10.1016/0378-1119(84)90110-0.
We have determined the nucleotide sequence of an 841-bp fragment derived from a segment of the human genome previously cloned by Chumakov et al. [Gene 17 (1982) 19-26] and Zabarovsky et al. [Gene 23 (1983) 379-384] and containing regions homologous to the viral mos gene probe. This sequence displays homology with part of the coding region of the human and murine c-mos genes, contains several termination codons, and is interrupted by two Alu-family elements flanked by short direct repeats. Probably, the progenitor of the human c-mos gene was duplicated approximately at the time of mammalian divergence, was converted to a pseudogene, and acquired insertions of two Alu elements.
我们已经确定了一段841个碱基对片段的核苷酸序列，该片段源自人类基因组的一个区段，此前由丘马科夫等人[《基因》17卷（1982年）第19 - 26页]和扎巴罗夫斯基等人[《基因》23卷（1983年）第379 - 384页]克隆，并且包含与病毒mos基因探针同源的区域。该序列与人及小鼠c - mos基因的部分编码区显示出同源性，包含几个终止密码子，并且被两个侧翼带有短直接重复序列的Alu家族元件打断。可能，人类c - mos基因的祖先是在哺乳动物分化时大约被复制的，之后转变为一个假基因，并获得了两个Alu元件的插入。
