Fujimura N, Yuasa K, Uema K, Kurokawa K
Jpn J Antibiot. 1984 Sep;37(9):1669-78.
Patients with chronic complicated urinary tract polymicrobial infections due to Pseudomonas aeruginosa and other bacteria were treated with cefsulodin using cefotiam or cefmenoxime as a concomitant drug. Each drug was given to the patients in daily dose of 1 or 2 g by drip infusion twice a day for 5 to 16 days. The results were as follows: Overall clinical efficacy was excellent in 7 cases (44%), moderate in 6 cases (38%) and poor in 3 cases (19%), the effectiveness rate being 81.3%. Bacteriologically, 38 strains (88.4%) were eradicated, 1 strain decreased and 4 strains unchanged out of the 43 clinical isolates from the patients. No side effects and no abnormalities of laboratory findings were observed.
患有由铜绿假单胞菌和其他细菌引起的慢性复杂性泌尿道混合感染的患者,接受了头孢磺啶治疗,同时使用头孢替安或头孢甲肟作为伴随药物。每种药物以每日1或2克的剂量通过静脉滴注,每天两次,给药5至16天。结果如下:总体临床疗效极佳的有7例(44%),中等的有6例(38%),差的有3例(19%),有效率为81.3%。细菌学方面,患者的43株临床分离菌中,38株(88.4%)被根除,1株减少,4株未改变。未观察到副作用和实验室检查结果异常。