Choline acetyltransferase activity and [3H]quinuclidinylbenzilate binding in brains of scrapie-infected hamsters.
作者信息
Masullo C, Pocchiari M, Gibbs C J, Gajdusek D C
出版信息
Neurosci Lett. 1984 Sep 28;51(1):87-92. doi: 10.1016/0304-3940(84)90267-2.
PMID:6096772
Abstract
Choline acetyltransferase (ChAT) activity and [3H]quinuclidinylbenzilate binding were studied in the brain of scrapie-infected hamsters and sham inoculated controls. Although scrapie-infected hamsters showed no reduction of ChAT activity compared to the controls, they showed a decrease in the affinity and maximum number of post-synaptic muscarinic receptors. Scrapie virus thus alters the cholinergic system at the post-synaptic rather than at the pre-synaptic level.
摘要
相似文献
1
Choline acetyltransferase activity and [3H]quinuclidinylbenzilate binding in brains of scrapie-infected hamsters.
Neurosci Lett. 1984 Sep 28;51(1):87-92. doi: 10.1016/0304-3940(84)90267-2.
2
Pre- and post-synaptic cholinergic dysfunction in aged rodent brain regions: new findings and an interpretative review.
Int J Dev Neurosci. 1990;8(6):689-708. doi: 10.1016/0736-5748(90)90063-8.
3
The distribution of cholinergic enzymes and 3H-QNB binding in smooth muscles of the cow stomach (Bos taurus).
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988;89(1):87-92. doi: 10.1016/0742-8413(88)90150-8.
4
Muscarinic binding and choline acetyltransferase activity in Parkinsonian subjects with reference to dementia.帕金森病患者中与痴呆相关的毒蕈碱结合及胆碱乙酰转移酶活性
Brain Res. 1982 Jan 28;232(1):129-39. doi: 10.1016/0006-8993(82)90615-1.
5
Cholinergic system in experimental rabies in mice.小鼠实验性狂犬病中的胆碱能系统。
Acta Virol. 1993 Dec;37(6):502-8.
6
Topographic distribution of choline acetyltransferase activity and muscarinic and nicotinic receptors in Parkinson brains.帕金森病患者大脑中胆碱乙酰转移酶活性以及毒蕈碱型和烟碱型受体的拓扑分布。
Neurochem Pathol. 1985 Winter;3(4):223-36.
7
Specific binding of the muscarinic antagonist [3H]quinuclidinyl benzilate is not associated with preganglionic motor neurons in the dorsal motor nucleus of the vagus.毒蕈碱拮抗剂[3H]喹核醇基苯甲酸酯的特异性结合与迷走神经背运动核中的节前运动神经元无关。
Neurochem Res. 1983 Jan;8(1):73-87. doi: 10.1007/BF00965655.
8
Serotoninergic system in scrapie-infected hamsters.患瘙痒病仓鼠的血清素能系统。
J Neurochem. 1985 Mar;44(3):862-8. doi: 10.1111/j.1471-4159.1985.tb12895.x.
9
Development of markers for cholinergic neurones in re-aggregate cultures of foetal rat whole brain in serum-containing and serum-free media: effects of triiodothyronine (T3).在含血清和无血清培养基中胎鼠全脑再聚集培养物中胆碱能神经元标志物的发育：三碘甲状腺原氨酸（T3）的作用
Br J Pharmacol. 1984 Sep;83(1):89-102. doi: 10.1111/j.1476-5381.1984.tb10123.x.
10
Comparison of [3H]pirenzepine and [3H]quinuclidinylbenzilate binding to muscarinic cholinergic receptors in rat brain.[3H]哌仑西平和[3H]喹核醇基苯甲酸酯与大鼠脑内毒蕈碱胆碱能受体结合的比较
J Pharmacol Exp Ther. 1984 Mar;228(3):648-55.
Zotero 插件