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噬菌体T4基因组中包含三个头部蛋白基因的片段的复杂转录模式。

The complex pattern of transcription in the segment of the bacteriophage T4 genome containing three of the head protein genes.

作者信息

Elliott T, Kassavetis G A, Geiduschek E P

出版信息

Virology. 1984 Dec;139(2):260-82. doi: 10.1016/0042-6822(84)90373-8.

Abstract

A detailed analysis of the temporal pattern of transcription in the gene 22-24 region of bacteriophage T4 has been made. Each of these three late genes has its own promoter, activated during the late phase of viral development. There is also late transcription of the opposite DNA strand across two of these late promoters. The 5' ends of these two sets of convergent transcripts have been mapped to sites designated Q22 and Q23. Middle (T4 gene mot product-dependent) transcription was found opposing the third late promoter, P24. An early promoter was mapped to the region between genes 23 and 24.

摘要

对噬菌体T4基因22 - 24区域转录的时间模式进行了详细分析。这三个晚期基因中的每一个都有其自身的启动子,在病毒发育的晚期被激活。在这两个晚期启动子的相反DNA链上也存在晚期转录。这两组反向转录物的5'端已被定位到指定为Q22和Q23的位点。发现中间(依赖T4基因mot产物)转录与第三个晚期启动子P24相反。一个早期启动子被定位到基因23和24之间的区域。

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