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病毒被口腔淋巴细胞吸收以及口腔多形核白细胞抗菌活性降低。

Absorption of viruses into oral lymphocytes and decreased antibacterial activity of oral polymorphonuclear leukocytes.

作者信息

Ongrádi J, Sallay K, Kulcsár G, Dán P, Horváth J, Nász I

出版信息

Acta Microbiol Hung. 1984;31(3):179-85.

PMID:6097084
Abstract

Antibacterial activity of the oral polymorphonuclear leukocytes and in vitro virus absorption by oral lymphocytes was studied in two patient groups and in controls. A slight decrease of phagocytosis was observed in those control cases and periodontitis patients where orolymphocytes and oral epithelial cells had absorbed viruses, but in the same subjects the bactericidal effect was significantly weaker. Periodontosis patients with a defect of polymorphonuclear cells did not exhibit such a difference. As in similar subjects the antibacterial activity was more frequently weak when their orolymphocytes carried latent viruses, the results suggest that certain individuals are prone to carry latent viruses in their lymphocytes. Lymphokines released from these carrier cells and concentrated locally might damage phagocytic leukocytes, resulting in serious local inflammation.

摘要

在两组患者及对照组中研究了口腔多形核白细胞的抗菌活性以及口腔淋巴细胞的体外病毒吸附情况。在口腔淋巴细胞和口腔上皮细胞吸收了病毒的对照组病例和牙周炎患者中,观察到吞噬作用略有下降,但在同一受试者中,杀菌效果明显较弱。多形核细胞有缺陷的牙周变性患者未表现出这种差异。由于在类似受试者中,当他们的口腔淋巴细胞携带潜伏病毒时,抗菌活性更常较弱,结果表明某些个体易于在其淋巴细胞中携带潜伏病毒。从这些携带细胞释放并在局部浓缩的淋巴因子可能会损害吞噬性白细胞,导致严重的局部炎症。

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Acta Microbiol Hung. 1984;31(3):179-85.
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引用本文的文献

1
The decreased antibacterial activity of oral polymorphonuclear leukocytes coincides with the occurrence of virus-carrying oral lymphocytes and epithelial cells.口腔多形核白细胞抗菌活性的降低与携带病毒的口腔淋巴细胞和上皮细胞的出现同时发生。
Folia Microbiol (Praha). 1987;32(5):438-47. doi: 10.1007/BF02887577.