麻醉犬电刺激下丘脑外侧引起的低血压特征

Characteristics of hypotension elicited by electrical stimulation of the lateralhypothalamusin anaesthetized dogs.

作者信息

van Bogaert A, Wellens D, van Bogaert P P, Martin J J, De Wilde A

出版信息

Arch Int Physiol Biochim. 1976 Feb;84(1):35-46. doi: 10.3109/13813457609072344.

Abstract

Electrical stimulation of the lateral hypothalamus near the paraventricular nucleus hypothalami, resulted in : hypotension, light bradycardia, decrease of the left ventricular systolic pressure without increase of the left ventricular end-diastolic pressure or left ventricular output, femoral vasodilatation and occasionally renal vasodilatation. The hypotensive reactions were potentiated by baroreceptor deafferentation. They were not blocked by anticholinergic, antihistaminic or antidopaminergic agents.

摘要

对下丘脑室旁核附近的下丘脑外侧区进行电刺激，结果如下：血压降低、轻度心动过缓、左心室收缩压下降，而左心室舒张末期压力或左心室输出量未增加，股血管扩张，偶尔肾血管也扩张。压力感受器去传入神经支配可增强降压反应。抗胆碱能、抗组胺或抗多巴胺能药物不能阻断这些反应。