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鳗鲡鳃上皮细胞质膜中依赖钙的磷酸酶和依赖钙的ATP酶活性——III. 催乳素诱导美洲鳗鲡高钙血症期间鳃部高亲和力钙ATP酶活性的刺激

Ca2+-dependent phosphatase and Ca2+-dependent ATPase activities in plasma membranes of eel gill epithelium--III. Stimulation of branchial high-affinity Ca2+-ATPase activity during prolactin-induced hypercalcemia in American eels.

作者信息

Flik G, Wendelaar Bonga S E, Fenwick J C

出版信息

Comp Biochem Physiol B. 1984;79(4):521-4. doi: 10.1016/0305-0491(84)90359-6.

DOI:10.1016/0305-0491(84)90359-6
PMID:6097400
Abstract

Infusions of ovine prolactin for 10 days induced hypercalcemia in unfed American eels, Anguilla rostrata LeSueur, that tentatively was related to stimulation of branchial Ca2+-uptake mechanisms. Analysis of ATPase activities in the plasma membranes of the branchial epithelium in prolactin treated eels showed a specific stimulation of high-affinity Ca2+-ATPase. The results of this study form further evidence that the high-affinity Ca2+-ATPase activity represents the Ca2+-pump of the branchial epithelium.

摘要

对未喂食的美洲鳗鱼（美洲鳗鲡，LeSueur）连续输注10天羊催乳素会引发高钙血症，这可能与鳃对钙离子摄取机制的刺激有关。对接受催乳素处理的鳗鱼鳃上皮细胞质膜中的ATP酶活性分析表明，高亲和力钙离子ATP酶受到了特异性刺激。本研究结果进一步证明，高亲和力钙离子ATP酶活性代表了鳃上皮细胞的钙离子泵。

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