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豚鼠实验性静脉血栓形成:肝素及影响血小板功能药物的作用(作者译)

[Experimental venous thrombosis in guinea pigs: effect of heparin and drugs affecting platelet function (author's transl)].

作者信息

Maffei F H, Pinto A M, Fabris V E, Lastória S, Rollo H D

出版信息

Rev Bras Pesqui Med Biol. 1977 Dec;10(6):369-78.

PMID:609774
Abstract

Thrombosis was induced in the jugular vein of guinea pigs by damage of the epithelium with a sclerosing solution. The effect of heparin, Dextran 70, acetylsalicylic acid, dypriridamole and phenilbutazone in preventing the development of the thrombus was investigated. Only heparin in high doses showed this effect.

摘要

用硬化溶液损伤上皮,在豚鼠颈静脉中诱发血栓形成。研究了肝素、右旋糖酐70、乙酰水杨酸、双嘧达莫和保泰松在预防血栓形成方面的作用。只有高剂量的肝素显示出这种作用。

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