Kuchino Y, Matsumoto M, Hosoda M, Hoshino H, Nishimura S
Nucleic Acids Symp Ser. 1984(15):29-32.
Administration of queuine into intact cells has an affected protein biosynthesis in vivo. In C3H2K mouse kidney cells, synthesis of a protein having a molecular weight of 45,000 was prevented by addition of queuine into the culture medium. In the case of SA-1 cells, which are variant cells of mouse mammary tumor cells, a protein whose molecular weight was 95,000 and located in the cytosol of its cells was changed to a more basic protein by administration of queuine.
将喹啉注入完整细胞会影响体内蛋白质的生物合成。在C3H2K小鼠肾细胞中，向培养基中添加喹啉可阻止分子量为45,000的蛋白质的合成。在SA-1细胞（小鼠乳腺肿瘤细胞的变异细胞）中，通过注入喹啉，一种分子量为95,000且位于其细胞胞质溶胶中的蛋白质变成了一种碱性更强的蛋白质。
