Funovics J, Függer R, Schulz F, Zöch G, Ulrich W
Zentralbl Chir. 1984;109(23):1473-81.
37 patients suffering from apudomas of the pancreas are reported (18 insulinomas, 6 isletcell-hyperplasias, 9 Zollinger-Ellison syndroms, 1 glucagonoma, 3 without hormone production). In preoperative localization computerized tomography and angiography were the best with 65% positive findings. Insulinomas were enucleated, all free of recidives. 50% of operated isletcell hyperplasias had a postoperative resisting hyperinsulinism. Either gastrectomy or tumour enucleation was performed in the Zollinger-Ellison syndrome. The five-years survival rate was 43%.
报告了37例胰腺APUD瘤患者(18例胰岛素瘤、6例胰岛细胞增生、9例佐林格-埃利森综合征、1例胰高血糖素瘤、3例无激素分泌)。术前定位检查中,计算机断层扫描和血管造影最佳,阳性发现率为65%。胰岛素瘤行摘除术,均无复发。50%接受手术的胰岛细胞增生患者术后存在持续性高胰岛素血症。佐林格-埃利森综合征患者行胃切除术或肿瘤摘除术。五年生存率为43%。