[Estrogenic vaginal creams and calciuria in postmenopausal women].

In a group of 25 post menopausal women 50 - 75 years old (mean 57,2 years) the urinary calcium creatinine ratio was examined before and after four months of vaginal estrogen cream application. Estrogen well absorbed by the vaginal epithelium, lowered calcium excretion in urine from 200,12 mg/100 ml before treatment to 172,76 mg during treatment. Urinary Ca/ce ratio decreased from 0,25 before to 0,19 during treatment. A statistically significant p less than 0,01. In the light of our findings, the treatment can be recommended to menopausal women at risk of developing osteoporosis, even is cases of hyperlipidemia or mild diabetes mellitus. It is wise to add dietary calcium and physical exercises.