Rochat H, Darbon H, Jover E, Martin M F, Bablito J, Couraud F
J Physiol (Paris). 1984;79(4):334-7.
Scorpion toxins are miniproteins that have been characterized with regard to their molecular properties including their pharmacological action. On these bases, toxins specific to mammals or to insects have been described and within the first category alpha- and beta-toxins identified. These toxins were chemically modified and used as molecular probes of the sodium channel. Thus, the interaction of the toxins with the pharmacological target could be followed and a better definition of this target could be obtained.
蝎毒素是一类小蛋白质，已根据其分子特性（包括药理作用）进行了表征。基于这些特性，已描述了对哺乳动物或昆虫具有特异性的毒素，并且在第一类中鉴定出了α-毒素和β-毒素。这些毒素经过化学修饰后用作钠通道的分子探针。因此，可以追踪毒素与药理靶点的相互作用，并能更好地定义该靶点。
