人类慢性美沙酮维持治疗期间促肾上腺皮质激素、皮质醇和β-内啡肽对甲吡酮试验的反应。
ACTH, cortisol and beta-endorphin response to metyrapone testing during chronic methadone maintenance treatment in humans.
作者信息
Kreek M J, Ragunath J, Plevy S, Hamer D, Schneider B, Hartman N
出版信息
Neuropeptides. 1984 Dec;5(1-3):277-8. doi: 10.1016/0143-4179(84)90081-7.
PMID:6099512
Abstract
Normal responses to metyrapone were observed in most steady-state methadone maintained treatment patients. These preliminary studies suggest that in recently detoxified methadone maintained treatment patients, there may be an exaggerated response of the hypothalamic-pituitary-adrenal axis to metyrapone.
摘要
在大多数接受美沙酮维持治疗的稳态患者中观察到对甲吡酮的正常反应。这些初步研究表明，在近期戒毒的美沙酮维持治疗患者中，下丘脑-垂体-肾上腺轴对甲吡酮的反应可能会过度。
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