Cellesi C, Rossolini A
Pediatr Med Chir. 1984 Jan-Feb;6(1):13-5.
The authors, after a review of some data about the actual poliomyelitis epidemiology in the world, point out the necessity of periodical checks for poliomyelitis vaccination. To this purpose, preliminary data of a research, undertaken in the province of Siena, into the effectiveness and innocuity of oral poliovirus vaccine, are reported. This evaluation has been made through isolation and identification of vaccinal polioviruses from stool after the first, second and then third dose of vaccine, and through titration of serum neutralizing antibodies. Results confirm the high effectiveness and innocuity of oral poliovirus vaccine, but suggest the opportuneness of some changes in the way of giving the oral vaccine.
作者在回顾了世界上有关脊髓灰质炎实际流行病学的一些数据后，指出了定期检查脊髓灰质炎疫苗接种情况的必要性。为此，报告了在锡耶纳省进行的一项关于口服脊髓灰质炎病毒疫苗有效性和安全性研究的初步数据。该评估是通过在接种第一剂、第二剂和第三剂疫苗后从粪便中分离和鉴定疫苗株脊髓灰质炎病毒，以及通过滴定血清中和抗体来进行的。结果证实了口服脊髓灰质炎病毒疫苗的高效性和安全性，但表明口服疫苗的接种方式有必要进行一些改变。
