Sarlangue J, Megraud F, Nelson J R, Martin C
Pediatrie. 1984 Dec;39(8):645-51.
Three cases of meningitis with E. coli and H. influenzae are reported. They illustrate the recrudescence and relapse in bacterial meningitis. After the failure of initial antibiotic therapy, the treatment by Cefotaxime allowed a good outcome in all the cases. On account of the bacteriological, pharmacological and clinical data the authors advise using Cefotaxime in first purpose in meningitis with common gram negative bacilli.
报告了3例大肠杆菌和流感嗜血杆菌引起的脑膜炎病例。它们说明了细菌性脑膜炎的复发和再发情况。在初始抗生素治疗失败后,使用头孢噻肟治疗使所有病例都取得了良好的疗效。基于细菌学、药理学和临床数据,作者建议在常见革兰氏阴性杆菌引起的脑膜炎中首先使用头孢噻肟。