内在膜蛋白的结晶

J Bioenerg Biomembr. 1984 Dec;16(5-6):321-33. doi: 10.1007/BF00743229.

After many years of discouraging failures, it is now possible to crystallize the intrinsic membrane proteins and to obtain structural information from diffraction studies on the crystals. The strategy for the crystallization consists of depletion of boundary phospholipids from the protein and complex formation with specific ligands.

经过多年令人沮丧的失败后，现在已能够使内在膜蛋白结晶，并从对晶体的衍射研究中获得结构信息。结晶的策略包括从蛋白质中去除边界磷脂以及与特定配体形成复合物。