头孢曲松对厌氧菌的体外活性比较
Comparative in vitro activity of ceftriaxone against anaerobic bacteria.
作者信息
Rolfe R D, Finegold S M
出版信息
Antimicrob Agents Chemother. 1982 Aug;22(2):338-41. doi: 10.1128/AAC.22.2.338.
Abstract
The in vitro activity of ceftriaxone was compared with those of other recently introduced beta-lactam antimicrobial agents (cefoperazone, cefotaxime, and moxalactam) and with those of cefoxitin, clindamycin, and metronidazole against 227 strains of anaerobic bacteria. The data obtained in this investigation suggest that ceftriaxone, like a majority of the new beta-lactam antimicrobial agents, may be of limited value in the treatment of serious infections involving anaerobic bacteria.
摘要
将头孢曲松的体外活性与其他近期推出的β-内酰胺类抗菌药物（头孢哌酮、头孢噻肟和拉氧头孢）以及头孢西丁、克林霉素和甲硝唑对227株厌氧菌的活性进行了比较。本次研究获得的数据表明，与大多数新型β-内酰胺类抗菌药物一样，头孢曲松在治疗涉及厌氧菌的严重感染方面可能价值有限。
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