蛋白质动力学

Dynamics of proteins.

作者信息

Karplus M

出版信息

Adv Biophys. 1984;18:165-90. doi: 10.1016/0065-227x(84)90011-x.

Abstract

Theoretical methods for studying protein motions have been outlined and some examples have been given. Simulation methods have shown that structural fluctuations in proteins cover a wide range in their magnitudes and time scales. Some indication of their biological role has been given, but the most important and interesting applications to protein function have to be made.

摘要

已概述了研究蛋白质运动的理论方法，并给出了一些示例。模拟方法表明，蛋白质中的结构波动在幅度和时间尺度上涵盖了很广的范围。已经给出了它们生物学作用的一些迹象，但对蛋白质功能最重要和最有趣的应用还有待开展。