Bisetti A, Livi E
Z Erkr Atmungsorgane. 1977 Aug;149(2):212-8.
A report is given on familial sarcoidosis in four cases. These 4 cases comprise one brother-sister and one mother-son relationship. Brother and sister were young persons in the acute stage (Löfgren-syndrome). In the other two cases diffuse fibroses accompanied by severe functional disturbances were to be observed. In both relationships clinical and radiological picture, course of the illness and response to the treatment were similar: favourable in the first, unfavourable in the second relationship. The frequency of familial occurrence is said to be 3.7% of all sarcoidosis cases.
报告了4例家族性结节病。这4例包括一对兄妹和一对母子。兄妹处于急性期（ Löfgren综合征），均为年轻人。另外两例观察到伴有严重功能障碍的弥漫性纤维化。在这两对亲属关系中，临床和放射学表现、病程及对治疗的反应相似：第一对亲属关系预后良好，第二对则预后不良。据报道，家族性发病在所有结节病病例中的发生率为3.7% 。
