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淋病奈瑟菌P9同基因变体产生的两种不同菌毛类型的生物学特性

Biological properties of two distinct pilus types produced by isogenic variants of Neisseria gonorrhoeae P9.

作者信息

Lambden P R, Robertson J N, Watt P J

出版信息

J Bacteriol. 1980 Jan;141(1):393-6. doi: 10.1128/jb.141.1.393-396.1980.

DOI:10.1128/jb.141.1.393-396.1980
PMID:6101593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC293609/
Abstract

Isogenic variants from a single strain of Neisseria gonorrhoeae were shown to produce two distinct types of pili. These pili, designated alpha and beta, differed in both subunit molecular weight and in ability to attach to buccal epithelial cells.

摘要

来自单一淋病奈瑟菌菌株的同基因变体被证明可产生两种不同类型的菌毛。这些菌毛,分别命名为α和β,在亚基分子量和附着于颊上皮细胞的能力方面均有所不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1a1/293609/634189d2d6ef/jbacter00562-0410-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1a1/293609/634189d2d6ef/jbacter00562-0410-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1a1/293609/634189d2d6ef/jbacter00562-0410-a.jpg

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Biological properties of two distinct pilus types produced by isogenic variants of Neisseria gonorrhoeae P9.淋病奈瑟菌P9同基因变体产生的两种不同菌毛类型的生物学特性
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本文引用的文献

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The preparation and properties of gonococcal pili.
J Gen Microbiol. 1977 Sep;102(1):169-77. doi: 10.1099/00221287-102-1-169.
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Hemagglutination by purified type I Escherichia coli pili.纯化的I型大肠杆菌菌毛的血细胞凝集作用。
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Gonococci exit apically and basally from polarized epithelial cells and exhibit dynamic changes in type IV pili.淋球菌从极化上皮细胞的顶端和基底离开,并在IV型菌毛中表现出动态变化。
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Roles of PilC and PilE proteins in pilus-mediated adherence of Neisseria gonorrhoeae and Neisseria meningitidis to human erythrocytes and endothelial and epithelial cells.PilC和PilE蛋白在淋病奈瑟菌和脑膜炎奈瑟菌菌毛介导的对人红细胞、内皮细胞及上皮细胞黏附中的作用。
Infect Immun. 1999 Feb;67(2):834-43. doi: 10.1128/IAI.67.2.834-843.1999.
7
Role of glycosylation at Ser63 in production of soluble pilin in pathogenic Neisseria.丝氨酸63位点糖基化在致病性奈瑟菌可溶性菌毛蛋白产生中的作用
J Bacteriol. 1999 Jan;181(2):656-61. doi: 10.1128/JB.181.2.656-661.1999.
8
Shared themes of antigenic variation and virulence in bacterial, protozoal, and fungal infections.细菌、原生动物和真菌感染中抗原变异与毒力的共同主题。
Microbiol Mol Biol Rev. 1997 Sep;61(3):281-93. doi: 10.1128/mmbr.61.3.281-293.1997.
9
Analysis of protein binding to the Sma/Cla DNA repeat in pathogenic Neisseriae.致病性奈瑟菌中蛋白质与Sma/Cla DNA重复序列结合的分析。
Nucleic Acids Res. 1997 Apr 1;25(7):1362-8. doi: 10.1093/nar/25.7.1362.
10
Variable opacity (Opa) outer membrane proteins account for the cell tropisms displayed by Neisseria gonorrhoeae for human leukocytes and epithelial cells.可变不透明度(Opa)外膜蛋白决定了淋病奈瑟菌对人类白细胞和上皮细胞所表现出的细胞嗜性。
EMBO J. 1993 Feb;12(2):641-50. doi: 10.1002/j.1460-2075.1993.tb05697.x.
4
Attachment role of gonococcal pili. Optimum conditions and quantitation of adherence of isolated pili to human cells in vitro.
J Clin Invest. 1978 Apr;61(4):931-43. doi: 10.1172/JCI109018.
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Attachment and ingestion of gonococci human neutrophils.淋球菌与人类中性粒细胞的黏附及吞噬作用。
Infect Immun. 1975 Mar;11(3):512-6. doi: 10.1128/iai.11.3.512-516.1975.
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Type I Escherichia coli pili: characterization of binding to monkey kidney cells.I型大肠杆菌菌毛:与猴肾细胞结合的特性
J Exp Med. 1977 Nov 1;146(5):1182-94. doi: 10.1084/jem.146.5.1182.