抗菌毛抗体对豚鼠皮下腔室中淋球菌存活的影响。
Effect of anti-pilus antibodies on survival of gonococci within guinea pig subcutaneous chambers.
作者信息
Lambden P R, Heckels J E, Watt P J
出版信息
Infect Immun. 1982 Oct;38(1):27-30. doi: 10.1128/iai.38.1.27-30.1982.
Abstract
Guinea pigs were immunized with either alpha or beta pili from Neisseria gonorrhoeae P9 before the inoculation of subcutaneous chambers with a mixture of variants having alpha, beta, gamma, or delta pili. Animals immunized with alpha pili showed significant protection, but those immunized with beta pili did not. The degree of protection could be correlated with the cross-reactivity of the antibodies produced to the heterologous pilus types.
摘要
在用含有α、β、γ或δ菌毛的变体混合物接种皮下腔室之前，豚鼠分别用淋病奈瑟菌P9的α或β菌毛进行免疫。用α菌毛免疫的动物表现出显著的保护作用，但用β菌毛免疫的动物则没有。保护程度与针对异源菌毛类型产生的抗体的交叉反应性相关。
相似文献
1
Effect of anti-pilus antibodies on survival of gonococci within guinea pig subcutaneous chambers.抗菌毛抗体对豚鼠皮下腔室中淋球菌存活的影响。
Infect Immun. 1982 Oct;38(1):27-30. doi: 10.1128/iai.38.1.27-30.1982.
2
The inability of Neisseria gonorrhoeae pili antibodies to confer immunity in subcutaneous guinea-pig chambers.淋病奈瑟菌菌毛抗体在豚鼠皮下腔室中无法赋予免疫力。
J Gen Microbiol. 1976 Jan;92(1):224-8. doi: 10.1099/00221287-92-1-224.
3
Antigenic heterogeneity associated with pilus aggregation and autoagglutinability in Neisseria gonorrhoeae.淋病奈瑟菌中与菌毛聚集和自身凝集性相关的抗原异质性。
J Gen Microbiol. 1980 Nov;121(1):195-202. doi: 10.1099/00221287-121-1-195.
4
Immunological and serological diversity of Neisseria gonorrhoeae: immunotyping of gonococci by cross-protein in guinea pig subcutaneous chambers.淋病奈瑟菌的免疫学和血清学多样性：豚鼠皮下腔室中通过交叉蛋白对淋球菌进行免疫分型
Infect Immun. 1976 Dec;14(6):1293-6. doi: 10.1128/iai.14.6.1293-1296.1976.
5
Protection against infection with Neisseria gonorrhoeae by immunization with outer membrane protein complex and purified pili.通过用外膜蛋白复合物和纯化菌毛进行免疫接种来预防淋病奈瑟菌感染。
J Infect Dis. 1977 Aug;136 Suppl:S132-7. doi: 10.1093/infdis/136.supplement.s132.
6
Role of anti-pilus antibodies in host defense against gonococcal infection studied with monoclonal anti-pilus antibodies.利用单克隆抗菌毛抗体研究抗菌毛抗体在宿主防御淋球菌感染中的作用。
Infect Immun. 1985 Sep;49(3):621-8. doi: 10.1128/iai.49.3.621-628.1985.
7
Immunological heterogeneity of pili of Neisseria gonorrhoeae.淋病奈瑟菌菌毛的免疫异质性
J Gen Microbiol. 1975 Jul;89(1):87-92. doi: 10.1099/00221287-89-1-87.
8
Immunization of guinea pigs with Neisseria gonorrhoeae: strain specificity and mechanisms of immunity.用淋病奈瑟菌对豚鼠进行免疫：菌株特异性及免疫机制。
J Gen Microbiol. 1977 May;100(1):159-66. doi: 10.1099/00221287-100-1-159.
9
Effect of anti-pilus antisera on virulence of variants of Neisseria gonorrhoeae for cultured epithelial cells.抗菌毛抗血清对淋病奈瑟菌变异株对培养上皮细胞毒力的影响。
J Gen Microbiol. 1982 May;128(5):1095-100. doi: 10.1099/00221287-128-5-1095.
10
Monoclonal antibodies to gonococcal pili: studies on antigenic determinants on pili from variants of strain P9.针对淋球菌菌毛的单克隆抗体：对P9菌株变体菌毛上抗原决定簇的研究
J Gen Microbiol. 1983 Jun;129(6):1965-73. doi: 10.1099/00221287-129-6-1965.
引用本文的文献
1
Experimental gonococcal genital tract infection and opacity protein expression in estradiol-treated mice.雌二醇处理小鼠的实验性淋球菌生殖道感染及不透明蛋白表达
Infect Immun. 1999 Nov;67(11):5699-708. doi: 10.1128/IAI.67.11.5699-5708.1999.
2
Multiple gonococcal pilin antigenic variants are produced during experimental human infections.在人类实验性感染期间会产生多种淋球菌菌毛抗原变体。
J Clin Invest. 1994 Jun;93(6):2744-9. doi: 10.1172/JCI117290.
3
Nonrepresentative PCR amplification of variable gene sequences in clinical specimens containing dilute, complex mixtures of microorganisms.在含有稀释的、复杂微生物混合物的临床标本中可变基因序列的非代表性PCR扩增。
J Clin Microbiol. 1994 Feb;32(2):464-8. doi: 10.1128/jcm.32.2.464-468.1994.
4
Interaction of pathogenic neisseriae with nonphagocytic cells.致病性奈瑟菌与非吞噬细胞的相互作用。
Clin Microbiol Rev. 1995 Jul;8(3):376-88. doi: 10.1128/CMR.8.3.376.
5
Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair.淋病奈瑟菌的诱变：缺乏易错修复。
J Bacteriol. 1984 Oct;160(1):288-93. doi: 10.1128/jb.160.1.288-293.1984.
6
Autoplaquing in Neisseria gonorrhoeae.
J Bacteriol. 1985 Oct;164(1):461-5. doi: 10.1128/jb.164.1.461-465.1985.
7
Mucosal and systemic immune responses in BALB/c mice to Bacteroides gingivalis fimbriae administered orally.BALB/c小鼠口服牙龈卟啉单胞菌菌毛后的黏膜和全身免疫反应
Infect Immun. 1989 Nov;57(11):3466-71. doi: 10.1128/iai.57.11.3466-3471.1989.
8
Structure and function of pili of pathogenic Neisseria species.致病性奈瑟菌属菌毛的结构与功能
Clin Microbiol Rev. 1989 Apr;2 Suppl(Suppl):S66-73. doi: 10.1128/CMR.2.Suppl.S66.
本文引用的文献
1
The role of outer membrane proteins in the survival of Neisseria gonorrhoeae P9 within guinea-pig subcutaneous chambers.外膜蛋白在淋病奈瑟菌P9于豚鼠皮下腔室内存活中的作用
J Gen Microbiol. 1981 Sep;126(1):63-7. doi: 10.1099/00221287-126-1-63.
2
Structural comparison of Neisseria gonorrhoeae outer membrane proteins.淋病奈瑟菌外膜蛋白的结构比较
J Bacteriol. 1981 Feb;145(2):736-42. doi: 10.1128/jb.145.2.736-742.1981.
3
Antigenic heterogeneity associated with pilus aggregation and autoagglutinability in Neisseria gonorrhoeae.淋病奈瑟菌中与菌毛聚集和自身凝集性相关的抗原异质性。
J Gen Microbiol. 1980 Nov;121(1):195-202. doi: 10.1099/00221287-121-1-195.
4
Immune-enhanced phagocytosis of Neisseria gonorrhoeae by macrophages: characterization of the major antigens to which opsonins are directed.巨噬细胞对淋病奈瑟菌的免疫增强吞噬作用：调理素所针对的主要抗原的特性
J Gen Microbiol. 1980 Dec;121(2):365-72. doi: 10.1099/00221287-121-2-365.
5
Biological properties of two distinct pilus types produced by isogenic variants of Neisseria gonorrhoeae P9.淋病奈瑟菌P9同基因变体产生的两种不同菌毛类型的生物学特性
J Bacteriol. 1980 Jan;141(1):393-6. doi: 10.1128/jb.141.1.393-396.1980.
6
Neisseria gonorrhoeae 3. Demonstration of presumed appendages to cells from different colony types.淋病奈瑟菌 3. 不同菌落类型细胞上假定附属物的展示。
Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;79(3):437-9. doi: 10.1111/j.1699-0463.1971.tb00086.x.
7
Studies on gonococcus infection. I. Pili and zones of adhesion: their relation to gonococcal growth patterns.淋病奈瑟菌感染的研究。I. 菌毛与黏附区：它们与淋病奈瑟菌生长模式的关系。
J Exp Med. 1971 Oct 1;134(4):886-906. doi: 10.1084/jem.134.4.886.
8
Resistance of Neisseria gonorrhoeae grown in vivo to ingestion and digestion by phagocytes of human blood.淋病奈瑟菌在体内生长时对人血吞噬细胞吞噬和消化的抗性。
J Gen Microbiol. 1976 Oct;96(2):341-50. doi: 10.1099/00221287-96-2-341.
9
The inability of Neisseria gonorrhoeae pili antibodies to confer immunity in subcutaneous guinea-pig chambers.淋病奈瑟菌菌毛抗体在豚鼠皮下腔室中无法赋予免疫力。
J Gen Microbiol. 1976 Jan;92(1):224-8. doi: 10.1099/00221287-92-1-224.
10
Protection against infection with Neisseria gonorrhoeae by immunization with outer membrane protein complex and purified pili.通过用外膜蛋白复合物和纯化菌毛进行免疫接种来预防淋病奈瑟菌感染。
J Infect Dis. 1977 Aug;136 Suppl:S132-7. doi: 10.1093/infdis/136.supplement.s132.
Zotero 插件