婴儿期进行饮食排除能预防食物过敏还是仅能推迟食物过敏？一项对375名儿童进行的鱼类和柑橘类过敏研究。

Does dietary elimination in infancy prevent or only postpone a food allergy? A study of fish and citrus allergy in 375 children.

作者信息

Saarinen U M, Kajosaari M

出版信息

Lancet. 1980 Jan 26;1(8161):166-7. doi: 10.1016/s0140-6736(80)90657-1.

Abstract

In a study of fish and citrus allergy these foods were strictly avoided in 177 children up to 1 year of age, whereas 152 children had started taking fish before age 6 months and 145 children had started taking citrus fruits beofre 3 months. Both fish and citrus allergy, defined by a positive challenge, were found at age 3 years in a similar frequency (about 3%) in children with and without the first-year elimination. The results suggest that food allergy in childhood can be postponed but not prevented by dietary elimination in infancy.

摘要

在一项关于鱼类和柑橘类过敏的研究中，177名1岁以下儿童严格避免食用这些食物，而152名儿童在6个月龄前开始食用鱼类，145名儿童在3个月龄前开始食用柑橘类水果。通过阳性激发试验定义的鱼类和柑橘类过敏，在3岁时，无论是否在第一年进行饮食排除，出现的频率相似（约3%）。结果表明，儿童期食物过敏可以通过婴儿期的饮食排除来推迟，但不能预防。