Nakasu Y, Nakasu S, Handa J, Takeuchi J
Surg Neurol. 1980 Feb;13(2):154-6.
Two cases of craniopharyngioma presenting with amenorrhea-galactorrhea syndrome due to hyperprolactinemia are reported. After operation and irradiation, the tumor reduced markedly in size. Coincidental decrease in plasma prolactin level and restoration of menstruation seem to support the view that the hypothalamic prolactin inhibiting factor (PIF) had played an important role in hyperprolactinemia in these two patients.
报告了两例因高催乳素血症而出现闭经-溢乳综合征的颅咽管瘤病例。手术和放疗后，肿瘤大小明显缩小。血浆催乳素水平的同时下降和月经的恢复似乎支持这样一种观点，即下丘脑催乳素抑制因子（PIF）在这两名患者的高催乳素血症中起了重要作用。
