通过给予吡哆醇使大鼠肝脏酪氨酸转氨酶在体内稳定。
Stabilization of rat liver tyrosine aminotransferase in vivo by pyridoxine administration.
作者信息
Snape B M, Badawy A A, Evans M
出版信息
Biochem J. 1980 Feb 15;186(2):625-7. doi: 10.1042/bj1860625.
Abstract
Administration of pyridoxine stabilizes rat liver tyrosine aminotransferase in vivo, whereas administration of cortisol, cyclic AMP, glucagon, insulin, tryptophan or tyrosine does not. The results of these and other experiments with pyridoxine are discussed in relation to the mechanisms of action of this vitamin on the activity of the enzyme.
摘要
在体内，给予吡哆醇可使大鼠肝脏酪氨酸转氨酶稳定，而给予皮质醇、环磷酸腺苷、胰高血糖素、胰岛素、色氨酸或酪氨酸则不能。结合该维生素对该酶活性的作用机制，讨论了这些以及其他有关吡哆醇实验的结果。
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J Pharmacol Exp Ther. 1970 Aug;174(2):283-9.
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Changes in hepatic levels of tyrosine aminotransferase messenger RNA during induction by hydrocortisone.氢化可的松诱导过程中肝脏中酪氨酸转氨酶信使核糖核酸水平的变化。
J Biol Chem. 1978 Jun 10;253(11):4009-15.
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Increase in hepatic tyrosine aminotransferase mRNA during enzyme induction by N6,O2'-dibutyryl cyclic AMP.N6,O2'-二丁酰环磷酸腺苷诱导酶时肝脏酪氨酸转氨酶信使核糖核酸的增加。
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Role of coenzyme in aminotransferase turnover.辅酶在转氨酶周转中的作用。
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