Jay S J, O'Neill R P, Goodman N, Penman R
Am J Med Sci. 1977 Nov-Dec;274(3):325-8.
A 47-year-old woman presented with cough, pleuritic chest pain and fever of three weeks duration. Although the patient lived in an area where blastomycosis is endemic, this diagnosis was not initially considered owing to the presence of consolidation and a large pleural effusion on the initial chest roentgenogram. Cultures of sputa, bronchial washings and pleural fluid documented the presence of pleuropulmonary infection with Blastomyces dermatitidis. Therapy with amphotericin B was associated with rapid clinical, roentgenographic and bacteriologic resolution of both pleural and parenchymal lung disease.
一名47岁女性,出现咳嗽、胸膜炎性胸痛及发热3周。尽管该患者居住在芽生菌病的地方性流行区域,但由于初次胸部X线片显示有实变及大量胸腔积液,最初未考虑该诊断。痰液、支气管灌洗及胸腔积液培养证实存在皮炎芽生菌引起的胸膜肺感染。两性霉素B治疗使胸膜和肺实质疾病在临床、影像学及细菌学方面均迅速好转。