Deniker P, Loo H, Zarifian E
Ann Med Psychol (Paris). 1980 Jan;138(1):103-13.
The new data on the use of antidepressant drugs concern:--a precise characterization of the therapeutic spectrum of the antidepressant, --the knowledge of the mechanism of action of the drug,--the biochemical profile of the depression,--the pharmacokinetic data about the efficient plasmatic level of the anti-depressant: it is important to take into account the metabolism of the drug and its route of administration,--the discovery of new antidepressants different from tricyclis and I.M.A.O. inhibitors.
——抗抑郁药物治疗谱的精确表征,——药物作用机制的知识,——抑郁症的生化特征,——关于抗抑郁药物有效血浆水平的药代动力学数据:考虑药物的代谢及其给药途径很重要,——发现不同于三环类药物和单胺氧化酶抑制剂的新型抗抑郁药物。