Guyotat J
Encephale. 1978;4(5 Suppl):533-9.
The author distinguishes inhibition as a symptom from inhibition as a processus in the three following situations: a) Antidepressants and melancholic inhibition: the action on inhibition is studied referring to Kielholz classification of antidepressants. The author points out the risk of suicide by suppressing inhibition. b) Antidepressants and chronical psychoses: the author compares effects of antidepressants and stimulating neuroleptics in these syndroms. He thinks that with the two types of psychotropic drugs, one can obtain a desinhibitory effect. But antidepressants can be better used in paranoid personnalities, loss of ego boundaries, and some schizophrenic-like syndroms, when neuroleptics seem to be more desinhibitory in hebephrenics. The author stresses the depressive core in these psychotic personnalities. c) The antidepressant effect has been studied in neurotic depressions. The author describes essentially cases with reinforcement of inhibition as a negative therapeutic reaction by antidepressants. It deals with neurotic depressions evoluting on narcissic personnality back ground.
a)抗抑郁药与忧郁性抑制:参照基尔霍尔茨对抗抑郁药的分类来研究抗抑郁药对抑制的作用。作者指出抑制被抑制会有自杀风险。b)抗抑郁药与慢性精神病:作者比较了抗抑郁药和刺激性抗精神病药物在这些综合征中的效果。他认为使用这两种精神药物都能获得去抑制作用。但是抗抑郁药更适用于偏执型人格、自我界限丧失以及一些类精神分裂症综合征,而抗精神病药物在青春期痴呆患者中似乎更具去抑制作用。作者强调这些精神病性人格中的抑郁核心。c)已对神经症性抑郁症的抗抑郁作用进行了研究。作者主要描述了抗抑郁药强化抑制作为一种消极治疗反应的病例。这些病例涉及在自恋人格背景下演变的神经症性抑郁症。