Kuzmits R, Seyfried H, Wolf A, Müller M M
Enzyme. 1980;25(3):148-52. doi: 10.1159/000459240.
Serum guanase activity was measured in 20 healthy adults and in 62 patients with acute viral hepatitis, chronic active hepatitis, chronic persistent hepatitis, liver cirrhosis and fatty liver. Guanase and gamma-GT in patients were elevated in 87 and 64%, respectively. Elevated guanase activities were found in most cases of acute viral hepatitis, as well as in chronic hepatopathies. In patients with acute viral hepatitis pathologic activities of guanase were found following partial or total normalization of other liver function tests.
对20名健康成年人以及62名患有急性病毒性肝炎、慢性活动性肝炎、慢性持续性肝炎、肝硬化和脂肪肝的患者进行了血清鸟嘌呤酶活性检测。患者中鸟嘌呤酶和γ-谷氨酰转移酶升高的比例分别为87%和64%。在大多数急性病毒性肝炎病例以及慢性肝病病例中均发现鸟嘌呤酶活性升高。在急性病毒性肝炎患者中,在其他肝功能检查部分或完全恢复正常后仍发现鸟嘌呤酶的病理活性。