Dupré A, Christol B, Bories M
Ann Dermatol Venereol. 1977 Oct;104(10):611-5.
The acquired fibro-keratoma is a benign fibro-epithelial tumor of acquired nature. I was set apart as a distinct entity in 1968 by Bart et al. who named it "acquired digital fibro-keratoma". It is predominantly, although not exclusively, located on the fingers and toes, near the phalangeal joints. The authors report 8 personal cases and make a short general review of the disease. The lesion is slightly prominent, well defined and surrounded by a hyperkeratotic collar. It protrudes on the surface of the skin much like a hernia. Histologically, it is a dermo-epidermal tumor. There is a proliferation of connective tissue under the papillomatous, hyperacanthotic and orthokeratotic epidermis. The mature collagen bundles, voluminous fibroblasts and numerous enlarged capillaries are parallel to the vertical axis of the tumor. The acquired fibrokeratoma must be differentiated from other cutaneous tumors, particularly fibromas and Koënen's tumors. The etiology is unknown. However, it was found in some cases that a trauma had contributed to the development of the tumor. The only possible treatment is surgical excision.
获得性纤维角化瘤是一种后天性的良性纤维上皮肿瘤。1968年，巴特等人将其作为一种独特的实体区分出来，并将其命名为“获得性指（趾）纤维角化瘤”。它主要（但并非仅仅）位于手指和脚趾的指（趾）间关节附近。作者报告了8例个人病例，并对该疾病进行了简短的综述。病变稍有突出，边界清晰，周围有角质增生性边缘。它像疝一样突出于皮肤表面。组织学上，它是一种真皮表皮肿瘤。在乳头瘤样、棘层肥厚和正角化的表皮下有结缔组织增生。成熟的胶原束、大量的成纤维细胞和许多扩张的毛细血管与肿瘤的垂直轴平行。获得性纤维角化瘤必须与其他皮肤肿瘤，特别是纤维瘤和科嫩肿瘤相鉴别。病因不明。然而，在一些病例中发现创伤促进了肿瘤的发生。唯一可能的治疗方法是手术切除。
