Rosser W W, Simms J G, Patten D W, Forster J
Can Med Assoc J. 1981 Jan 15;124(2):147-53.
Indications for and dosages of four commonly prescribed benzodiazepines were recorded at a family medicine centre with the aid of a computerized data collection system. Four guidelines were then developed for appropriate prescribing of these drugs: (a) benzodiazepines should be used less frequently with increasing age; (b) short-acting drugs are preferable to long-acting drugs; (c) patients 65 years of age and over should receive half the daily dose prescribed for younger patients; and (d) use of these drugs for more than 1 month should be discouraged. After a year's observation it was evident that none of the guidelines were being followed. The 30 physicians in the practice were then informed of the findings by an educational program. Another 6 months of observation showed a reduction in the prescribing of benzodiazepines to patients 65 years of age and over, a significant shift to the use of short-acting benzodiazepines, and some reduction in the daily dose and duration of administration of diazepam. Thus, such a review of drug prescribing in family practice can be a practical and effective method of improving prescribing patterns.
在一个家庭医疗中心,借助计算机化数据收集系统记录了四种常用苯二氮䓬类药物的适应证和剂量。随后制定了四项关于合理使用这些药物的指南:(a) 随着年龄增长,应减少苯二氮䓬类药物的使用频率;(b) 短效药物优于长效药物;(c) 65岁及以上患者的日剂量应为年轻患者规定剂量的一半;(d) 不鼓励使用这些药物超过1个月。经过一年的观察,发现没有一项指南得到遵循。随后通过一个教育项目将这些结果告知了该诊所的30名医生。又经过6个月的观察,发现65岁及以上患者的苯二氮䓬类药物处方量有所减少,短效苯二氮䓬类药物的使用有显著转变,地西泮的日剂量和用药时长也有所减少。因此,这种对家庭医疗中药物处方的审查可以成为改善处方模式的一种切实有效的方法。