Cohen A, Hagan A D, Watkins J, Mitas J, Schvartzman M, Mazzoleni A, Cohen I M, Warren S E, Vieweg W V
Am J Cardiol. 1981 Feb;47(2):335-41. doi: 10.1016/0002-9149(81)90406-9.
Seventy-three hypertensive patients were evaluated with M mode and two dimensional echocardiography. Left ventricular hypertrophy was found in 37 patients (51 percent); 29 had concentric hypertrophy and the remaining 8 had disproportionate septal thickening. Factors that did not influence the distribution of patients in the group with left ventricular hypertrophy and normal subjects included (1) duration of hypertension, (2) level of blood pressure, (3) age, (4) body surface area, and (5) race. More of the patients who had a normal left ventricular mass (32 or 89 percent) than of those who had hypertrophy (22 or 59 percent) were receiving two or more antihypertensive drugs. Electrocardiography was very insensitive in identifying left ventricular hypertrophy in these patients. The presence of increased left ventricular mass was associated with a greater incidence of other target organ disease.
73名高血压患者接受了M型和二维超声心动图检查。37名患者（51%）发现左心室肥厚；29例为向心性肥厚，其余8例为室间隔不成比例增厚。不影响左心室肥厚组患者和正常受试者分布的因素包括：（1）高血压病程，（2）血压水平，（3）年龄，（4）体表面积，（5）种族。左心室质量正常的患者（32例或89%）比左心室肥厚的患者（22例或59%）服用两种或更多抗高血压药物的更多。心电图在识别这些患者的左心室肥厚方面非常不敏感。左心室质量增加与其他靶器官疾病的发生率较高有关。
