慢性精神分裂症患者中，抗精神病药物对血小板单胺氧化酶可能产生的影响。
A probable neuroleptic effect on platelet monoamine oxidase in chronic schizophrenic patients.
作者信息
DeLisi L E, Wise C D, Bridge T P, Rosenblatt J E, Wagner R L, Morihisa J, Karson C, Potkin S G, Wyatt R J
出版信息
Psychiatry Res. 1981 Feb;4(1):95-107. doi: 10.1016/0165-1781(81)90013-5.
PMID:6111821
Abstract
Platelet monoamine oxidase activity (MAO) was studied serially over time in 16 chronic schizophrenic patients when medication free and then when medicated. Thirteen of the 16 patients had significant decreases in platelet MAO activity following neuroleptic drug treatment. The change in MAO activity was found to be correlated with response to treatment and to dose of medication.
摘要
对16名慢性精神分裂症患者在未服药及服药时的血小板单胺氧化酶活性（MAO）进行了长期的连续研究。16名患者中有13名在接受抗精神病药物治疗后血小板MAO活性显著下降。发现MAO活性的变化与治疗反应及药物剂量相关。
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