无药物治疗和药物治疗的精神分裂症患者的人血小板单胺氧化酶
Human platelet MAO in drug-free and medicated schizophrenic patients.
作者信息
Friedhoff A J, Miller J C, Weisenfreund J
出版信息
Am J Psychiatry. 1978 Aug;135(8):952-5. doi: 10.1176/ajp.135.8.952.
PMID:27104
Abstract
The authors compared platelet monoamine oxidase activity in drug-free chronic and acute schizophrenic patients, medicated chronic schizophrenic patients, and normal controls. A significant decrement in MAO activity was found only in medicated chronic schizophrenic patients. The possible mechanism for this finding is discussed.
摘要
作者比较了未用药的慢性和急性精神分裂症患者、用药的慢性精神分裂症患者以及正常对照者的血小板单胺氧化酶活性。仅在用药的慢性精神分裂症患者中发现单胺氧化酶活性显著降低。本文讨论了这一发现的可能机制。
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