Baron M, Gruen R, Levitt M, Kane J
Psychiatry Res. 1982 Oct;7(2):179-87. doi: 10.1016/0165-1781(92)90091-g.
Activity levels of platelet monoamine oxidase (MAO) and plasma amine oxidase (PAO) were determined in eight chronic schizophrenic patients who had been treated with neuroleptic drugs for 3 months. The mean reduction in platelet MAO activity was 18.6%. The extent of decrease was statistically significant. The reduction in enzyme activity was unrelated to serum iron levels. PAO activity was unaltered. The implications for schizophrenia research are discussed.
测定了8例接受抗精神病药物治疗3个月的慢性精神分裂症患者的血小板单胺氧化酶（MAO）和血浆胺氧化酶（PAO）的活性水平。血小板MAO活性平均降低了18.6%。降低程度具有统计学意义。酶活性的降低与血清铁水平无关。PAO活性未改变。文中讨论了这些结果对精神分裂症研究的意义。
