Coxhead C E, Inskip H, Meade T W, North W R, Troup J D
Lancet. 1981 May 16;1(8229):1065-8. doi: 10.1016/s0140-6736(81)92238-8.
Four treatments for sciatic symptoms--traction, exercises, manipulation, and corset--were assessed in a randomised controlled trial in 322 outpatients. The design was factorial. There were thus sixteen treatment groups, enabling a comparison of combinations of methods as well as of individual methods. Treatment lasted for four weeks. Patients were reviewed at the end of this period and at four and sixteen months after entry to the trial. Progress was measured by the patient's account of symptomatic improvement or deterioration and by return to work or normal activities. At four weeks each of the treatments was associated with a small degree of benefit over and above the high rate of spontaneous improvement. For manipulation, the benefit was statistically significant on one of the scales used to measure progress. There was a significant increase in symptomatic improvement with increasing numbers of treatments used in combination. This was complemented by a clear tendency for those who had received fewer types of treatment during the trial to have further treatment in the ensuing three months. There were no beneficial effects of treatment detectable at four or sixteen months. In the short-term, active physiotherapy with several treatments appears to be of value in the outpatient management of patients with sciatic symptoms, but it does not seem to confer any longer-term benefit.
在一项针对322名门诊患者的随机对照试验中,对坐骨神经症状的四种治疗方法——牵引、运动、手法治疗和束腹带——进行了评估。该设计为析因设计。因此共有16个治疗组,能够对方法组合以及单个方法进行比较。治疗持续四周。在这段时间结束时以及进入试验后的四个月和十六个月对患者进行复查。通过患者对症状改善或恶化的描述以及恢复工作或正常活动来衡量进展情况。四周时,每种治疗方法除了自发改善率较高外,还带来了一定程度的益处。对于手法治疗,在用于衡量进展的一个量表上,益处具有统计学意义。联合使用的治疗方法数量增加,症状改善显著增加。这一点得到了补充,即在试验期间接受治疗类型较少的患者在随后三个月有进一步接受治疗的明显趋势。在四个月或十六个月时未检测到治疗的有益效果。短期内,几种治疗方法的积极物理治疗似乎对坐骨神经症状患者的门诊管理有价值,但似乎没有带来任何长期益处。