Skalicky M, Hofecker G, Kment A, Niedermüller H
Aktuelle Gerontol. 1981 Jan;11(1):4-7.
The capacity of age parameters to discriminate between groups or individuals of different biological age was investigated in the course of a long-term cohort study. 23 age parameters measured in 71 male Sprague-Dawley rats at the ages of 10, 17, 25 and 30 months, were submitted to a stepwise discriminant analysis. An optimal simultaneous discrimination between the four age groups was obtained by 3 discriminant functions with scores of 89.8%, 6.2% and 4%, with a correct classification of 98,6% of all individuals. Three analyses of successive age groups (10--17, 17--25, 25--30 months) resulted in a 100% correct classification by one function each. However, it turned out that in different phases of senescence an optimal discrimination between individuals or groups of different biological age is obtained by distinct combinations and weights of the parameters.
在一项长期队列研究过程中，对年龄参数区分不同生物学年龄组或个体的能力进行了研究。在71只10、17、25和30月龄的雄性斯普拉格-道利大鼠中测量的23个年龄参数，被进行逐步判别分析。通过3个判别函数对四个年龄组进行了最佳同时判别，得分分别为89.8%、6.2%和4%，所有个体的正确分类率为98.6%。对连续年龄组（10 - 17、17 - 25、25 - 30月龄）的三次分析，每次均通过一个函数实现了100%的正确分类。然而，结果表明，在衰老的不同阶段，通过参数的不同组合和权重可实现对不同生物学年龄个体或组的最佳判别。
