Hofecker G, Skalicky M, Kment A, Niedermüller H
Aktuelle Gerontol. 1981 Jan;11(1):8-11.
Biological age may be defined at the state of the organism as a whole which is characteristic of the respective chronological age. Usually, it is estimated by multivariate analysis of a battery of age parameters. However, this procedure requires the knowledge of the regularities of multicellular ageing since interferences about the behaviour of the total system from its subsystems may only drawn when the regularities of the total system are understood. By means of the ageing of the rat, the possibility is demonstrated to study these regularities by factor analysis. As a result, primary and system-specific secondary aging processes are postulated which are expressed to various extents in the individual age parameters.
生物学年龄可以定义为整个生物体的状态,它具有相应的实足年龄的特征。通常,它是通过对一系列年龄参数进行多变量分析来估计的。然而,这个过程需要了解多细胞衰老的规律,因为只有当整个系统的规律被理解时,才能从其子系统对整个系统的行为进行干扰推断。通过大鼠的衰老过程,证明了通过因子分析研究这些规律的可能性。结果,假定了初级和系统特异性的次级衰老过程,这些过程在各个年龄参数中以不同程度表现出来。