Chan M K, Baillod R A, Chuah P, Sweny P, Raftery M J, Varghese Z, Moorhead J F
Lancet. 1981 Jun 27;1(8235):1409-12. doi: 10.1016/s0140-6736(81)92582-4.
Patients on continuous ambulatory peritoneal dialysis (CAPD) were studied for three years. 29 of them who had been on CAPD for six months or more were compared with patients on intermittent peritoneal dialysis (IPD) and on haemodialysis (HD). CAPD patients had significantly higher levels of HDL-cholesterol than HD patients. Urea, potassium, phosphate, and urate levels were significantly lower, and haemoglobin levels significantly higher, than in the IPD and HD groups. 43 CAPD patients studied had a peritonitis rate of 2.22 episodes per patient-year. CAPD offers an alternative form of dialysis to those unsuitable for HD, but until peritonitis rates can be reduced CAPD cannot rival HD as a long-term treatment.
对接受持续性非卧床腹膜透析(CAPD)的患者进行了为期三年的研究。将其中29名已接受CAPD治疗六个月或更长时间的患者与接受间歇性腹膜透析(IPD)和血液透析(HD)的患者进行了比较。CAPD患者的高密度脂蛋白胆固醇水平显著高于HD患者。与IPD组和HD组相比,尿素、钾、磷酸盐和尿酸水平显著更低,血红蛋白水平显著更高。在接受研究的43名CAPD患者中,腹膜炎发生率为每位患者每年2.22次发作。CAPD为那些不适合HD的患者提供了一种替代透析方式,但在腹膜炎发生率能够降低之前,CAPD作为一种长期治疗方法无法与HD相媲美。