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通过对其宫缩抑制作用的靶向记录证明乙基肾上腺素(Effortil)的β-2-肾上腺素能活性(作者译)

[Proof of beta-2-adrenergic activity of etilefrin (effortil) via aimed recording of its tocolytic action (author's transl)].

作者信息

Hägele D, Berg D

出版信息

Z Geburtshilfe Perinatol. 1981 Apr;185(2):81-3.

PMID:6114599
Abstract

In 21 normal deliveries the intrauterine pressure was measured continuously during the first stage of labor. Thus the tocolytic efficiency of Etilefrin was revealed. Intensity and duration of the tocolytic effect were related to the dose. Pressure and frequency of the contractions were diminished. Therefore these results are conclusive that Etilefrin, generally given for its alpha- and beta 1 mimetic effects, has an additional beta 2-mimetic and tocolytic component.

摘要

在21例正常分娩中,在第一产程期间连续测量宫内压。由此揭示了乙苯福林的宫缩抑制效率。宫缩抑制作用的强度和持续时间与剂量有关。宫缩的压力和频率降低。因此,这些结果确凿地表明,通常因其α和β1拟交感神经效应而给予的乙苯福林具有额外的β2拟交感神经和宫缩抑制成分。

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