Stoianov E, Marinova M, Stîrbova M
Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir. 1981 May-Jun;30(3):225-30.
The paper presents the author's experience in post-anesthetic decurarization with a new antagonist of competitive curare. Presented for the first time in 1970, 4-amino-pyridine was found o tbe a substance with a different mode of action than that of reversible inhibitors of cholinesterase, without parasympaticomimetic effects, and without untoward effects on the cardio-circulatory function. It also has a central analeptic effect. This is why the authors consider the new drug as a powerful means for reversing the competitive neuromuscular blockage.
本文介绍了作者使用一种新型竞争性箭毒拮抗剂进行麻醉后脱箭毒作用的经验。4-氨基吡啶于1970年首次被提出，它是一种作用方式与可逆性胆碱酯酶抑制剂不同的物质，没有拟副交感神经作用，对心血管功能也没有不良影响。它还具有中枢兴奋作用。这就是为什么作者认为这种新药是逆转竞争性神经肌肉阻滞的有力手段。
