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[缓激肽与心血管系统受体相互作用的参数]

[Parameters of bradykinin interaction with cardiovascular system receptors].

作者信息

Kiselev V I, Panchenko A L

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1981 Sep;67(9):1342-7.

PMID:6117487
Abstract

The equation describing kinetics of interaction between bradykinin and cardiovascular receptors resembles the equations describing depressive adrenergic and some cholinergic reactions in dogs, rabbits and white rats. In this study of bradykinin receptor state, in order to describe quantitatively hypotensive action of different bradykinin doses on interaction of this peptide with receptors, bradykinin had to be injected intraaortally. The data obtained revealed that the greatest efficiency of kininergic reaction occurred in dogs whereas the least--in white rats.

摘要

描述缓激肽与心血管受体相互作用动力学的方程类似于描述犬、兔和白鼠中去甲肾上腺素能和某些胆碱能反应抑制的方程。在这项关于缓激肽受体状态的研究中,为了定量描述不同剂量缓激肽对该肽与受体相互作用的降压作用,必须经主动脉内注射缓激肽。所获得的数据表明,激肽能反应的最大效率出现在犬中,而最小效率出现在白鼠中。

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[Parameters of bradykinin interaction with cardiovascular system receptors].[缓激肽与心血管系统受体相互作用的参数]
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