Kiselev V I, Lebedev N M
Fiziol Zh SSSR Im I M Sechenova. 1983 Mar;69(3):386-90.
The reactions of cardiovascular system at various intensities of kininogenesis were studied with the aid od dose--effect curves of bradykinin hypotensive action. Correlations were found between the intensity of kinin--induced reaction and the level of some components of the blood Kallikrein-kinin system. Activation of kininogenesis was accompanied by a decrease of kinin-reactivity whereas inhibiton of kinin formation was followed by an augmentation of the hypotensive kinin-induced reaction.
借助缓激肽降压作用的剂量-效应曲线,研究了不同激肽生成强度下心血管系统的反应。发现激肽诱导反应的强度与血液激肽释放酶-激肽系统某些成分的水平之间存在相关性。激肽生成的激活伴随着激肽反应性的降低,而激肽形成的抑制则伴随着激肽诱导的降压反应增强。