[Propafenon-induced cholestatic liver injury--a further example for allergic drug hepatitis (author's transl)].

In the course of cholestatic liver injury after propafenonhydrochloride medication, a high increase of the glutamatedehydrogenase up to the twenty fold of the normal range was followed by a marked raise of SGOT and SGPT. Cholestatic enzymes like gamma-glutamyl transpeptidase and alkaline phosphatase reached their maxima a week later. Within two weeks the hepatic cell enzymes and within four weeks the cholestatic enzymes have returned spontaneously to normal.