Gamma-glutamyl transpeptidase and high-density lipoproteins cholesterol in male problem drinkers: advantages of a composite index for predicting alcohol consumption.

Forty male problem drinkers, participants of a treatment follow-up study, were assessed for levels of gamma-glutamyl transpeptidase (GGTP) and high-density lipoproteins cholesterol (HDL-C) in relationship to self-reported alcohol consumption over the previous 3-week period. A composite index of GGTP and HDL-C was superior to GGTP or HDL-C alone in discriminating abstinent/light, moderate, and heavy drinkers.