Takashima S, Matsui A, Fujii Y, Nakamura H
Brain Dev. 1981;3(4):365-74. doi: 10.1016/s0387-7604(81)80065-4.
The autopsy report of the juvenile type of metachromatic leukodystrophy is rare. The clinical and pathological difference between the juvenile and the late infantile type of metachromatic leukodystrophy was described. Loss of myelin sheaths was much less in the brain stem and spinal cord in the juvenile type than in the late infantile type, although that of the roots or cranial and spinal nerves was marked similarly in both types. The relationship of these pathological findings to clinical signs and laboratory data was discussed.
青少年型异染性脑白质营养不良的尸检报告很少见。本文描述了青少年型和晚婴儿型异染性脑白质营养不良在临床和病理上的差异。青少年型患者脑干和脊髓的髓鞘脱失程度远低于晚婴儿型，尽管两种类型神经根、颅神经及脊神经的髓鞘脱失均较明显。文中还讨论了这些病理表现与临床症状及实验室数据之间的关系。
