Zefirov A L
Biull Eksp Biol Med. 1981 Oct;91(10):389-92.
Changes in the quantum content of end plate potentials (EPPs) were studied in experiments on the frog sartorius muscle in the course of a gradual increase in stimulation frequency (frequency facilitation). It was shown that the frequency facilitation coefficient does not depend on the initial quantum content of EPPs but is in good agreement with the initial frequency of miniature EPPs and in bad agreement with their amplitude. The frequency facilitation is accompanied by the growth of the statistical binomial parameters P and n. The increase in P parameters is consequent of interference in P changes during the second component of facilitation after the single impulse. The growth of n is accounted for by the summation of the n increase during the first component of facilitation the time course of which is prolonged on repetitive stimulation.
在青蛙缝匠肌实验中，随着刺激频率逐渐增加（频率易化），研究了终板电位（EPP）的量子含量变化。结果表明，频率易化系数并不取决于EPP的初始量子含量，而是与微小EPP的初始频率高度吻合，与它们的幅度则不太相符。频率易化伴随着统计二项式参数P和n的增长。P参数的增加是由于单次冲动后易化第二个成分期间P变化的干扰所致。n的增长是由于易化第一个成分期间n的增加的总和，其时间进程在重复刺激时会延长。
