Giwa-Osagie O F, Newton J R, Larcher V
Int J Gynaecol Obstet. 1981 Aug;19(4):267-70. doi: 10.1016/0020-7292(81)90073-4.
Over a 10-year period, there were nine pregnancies in six myasthenic patients. In six of the nine pregnancies, there was an exacerbation of the disease, usually during the second trimester; in two pregnancies, drug requirements did not alter. One patient improved during pregnancy. Labor was efficient and uneventful, resulting in nine live babies, including one set of twins. Breastfeeding is not contra-indicated. The previously reported puerperal deterioration of myasthenia gravis is not a feature of this series.
在10年期间,6例重症肌无力患者共怀孕9次。9次怀孕中有6次病情加重,通常在孕中期;2次怀孕时药物需求未改变。1例患者在孕期病情改善。分娩顺利,产下9名活婴,包括一对双胞胎。母乳喂养并非禁忌。先前报道的重症肌无力产后病情恶化在本系列中并非特征表现。