Rolbin W H, Levinson G, Shnider S M, Wright R G
Anesth Analg. 1978 Jul-Aug;57(4):441-7. doi: 10.1213/00000539-197807000-00013.
Three pregnant patients with myasthenia gravis are presented and anesthetic considerations discussed. The course of myasthenia gravis is highly variable and unpredictable during pregnancy. Anticholinesterase therapy should be maintained during labor, and the IM route of administration is preferred. Exacerbations very often occur in the immediate postpartum period. Regional anesthesia is preferred for vaginal delivery. In the case of cesarean section, general anesthesia may be preferable. Neonatal myasthenia gravis is a transient syndrome that appears in 20 to 30% of the newborns of myasthenic mothers.
本文介绍了三名患有重症肌无力的孕妇，并讨论了麻醉相关注意事项。重症肌无力在孕期的病程高度可变且不可预测。分娩期间应维持抗胆碱酯酶治疗，且首选肌肉注射给药途径。产后即刻常出现病情加重。阴道分娩首选区域麻醉。剖宫产时，全身麻醉可能更可取。新生儿重症肌无力是一种短暂性综合征，见于20%至30%患重症肌无力母亲的新生儿。
